Taxim-O/Taxim-O 400/Taxim-O Kids Drug Interactions

Taxim-O/Taxim-O 400: Carbamazepine: Elevated carbamazepine levels have been reported in postmarketing experience when cefixime is administered concomitantly. Drug monitoring may be of assistance in detecting alterations in carbamazepine plasma concentrations.
Warfarin and Anticoagulants: Increased prothrombin time, with or without clinical bleeding, has been reported when cefixime is administered concomitantly.
Drug/Laboratory Test Interactions: A false-positive reactions for ketones in the urine may occur with tests using nitroprusside but not with those using nitroferricyanide. The administration of cefixime may result in a false-positive reaction for glucose in the urine using Clinitest, Benedict's solution, or Fehling's solution. A false-positive direct Coomb's test has been reported during treatment with other cephalosporin antibiotics; therefore, it should be recognized that a positive Coomb's test may be due to the drug.
Taxim-O Kids: Care should be exercised in patients receiving anticoagulants and cefixime due to the possibility that cefixime may increase prothrombin times.